Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[2-hydroxy-4-(2-methylpropoxy)phenyl](4-hydroxyphenyl)methanone | compound shows inhibitory activity against papain is a potent inhibitor of CPB2.8, CPB3.0 and cruzain, showing noncompetitive inhibition mechanism | Leishmania mexicana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania mexicana | P36400 | isoform CPB2.8 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
amastigote | - |
Leishmania mexicana | - |
Synonyms | Comment | Organism |
---|---|---|
CPB2.8 | - |
Leishmania mexicana |
CPB3.0 | - |
Leishmania mexicana |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0029 | - |
isoform CPB2.8, pH 5.5, 37°C | Leishmania mexicana | [2-hydroxy-4-(2-methylpropoxy)phenyl](4-hydroxyphenyl)methanone | |
0.0043 | - |
isoform CPB3.0, pH 5.5, 37°C | Leishmania mexicana | [2-hydroxy-4-(2-methylpropoxy)phenyl](4-hydroxyphenyl)methanone |